Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hoxXhoxX-like protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1024; Belongs to the enoyl-CoA hydratase/isomerase family. (565 aa)    
Predicted Functional Partners:
evgS
Sensor protein evgS precursor; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 0.799
nusB
N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.
  
  
 0.798
CV_1621
Probable sensor/response regulatory hybrid protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 0.793
CV_1951
Probable two-component sensor; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 0.792
CV_2643
Probable sensor/response regulator hybrid; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 0.792
CV_3248
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 0.792
CV_3503
Probable sensor/response regulator hybrid; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 0.788
rplB
50S ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
  
 
 0.787
CV_1579
Probable two-component hybrid sensor and regulator; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0784.
  
 0.785
CV_1581
Probable sensor/response hybrid; Identified by sequence similarity; putative; ORF located using Blastx/COG0784.
  
 0.782
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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