Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
IMPOrganic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. (753 aa)    
Predicted Functional Partners:
surA
Survival protein surA precursor; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
 
  
 0.950
rlpB
Rare lipoprotein B precursor; Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane; Belongs to the LptE lipoprotein family.
 
 
 
 0.948
lptA
Conserved hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane.
 
 
 0.919
CV_4228
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG3178.
 
     0.837
bamA
Probable outer membrane protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.836
CV_2915
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0795.
 
  
 0.830
omlA
Outer membrane lipoprotein OmlA; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.801
pdxA
Pyridoxal phosphate biosynthesis protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
  
  
 0.796
lolA
Outer membrane lipoproteins carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane).
  
   
 0.786
lpxA
acyl-[acyl-carrier-protein]-UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
  
 0.754
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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