STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (361 aa)    
Predicted Functional Partners:
pyrD
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.988
pyrB
Aspartate carbamoyltransferase catalytic chain; Identified by sequence similarity; putative; ORF located using Blastx/COG0540; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
 
 0.986
pydA
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.986
pyrI
Aspartate carbamoyltransferase; Involved in allosteric regulation of aspartate carbamoyltransferase.
   
 
  0.953
carB
Carbamoyl-phosphate synthase large chain; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0458; Belongs to the CarB family.
   
  
 0.854
codB
Purine cytosine permease-like protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1457/TC:2.A.39.2.1; Belongs to the purine-cytosine permease (2.A.39) family.
   
    0.801
CV_4331
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0425; Belongs to the sulfur carrier protein TusA family.
       0.796
carA
Carbomyl phosphate synthetase small subunit; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0505; Belongs to the CarA family.
   
  
 0.766
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
  
  
 0.640
guaA
GMP synthetase; Catalyzes the synthesis of GMP from XMP.
   
  
 0.631
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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