Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
aroPAromatic amino acid transport protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1113/TC:2.A.3.1.3. (456 aa)    
Predicted Functional Partners:
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0157; Belongs to the NadC/ModD family.
      
 0.702
pheA
Chorismate mutase/prephenate dehydratase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1605.
      
 0.636
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
      
 0.606
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
      
 0.528
trpC
Indole-3-glycerol phosphate synthase protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0134; Belongs to the TrpC family.
      
 0.496
CV_4369
Probable sodium/chloride ion channel; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0733/TC:2.A.22.5.1; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.
     
 0.483
aroG
Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
      
 0.434
aroF
2-dehydro-3-deoxy-phosphoheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
      
 0.433
ptsH
Sugar transport PTS system phosphocarrier protein HPR; Identified by sequence similarity; putative; ORF located using Blastx/COG1925.
      
 0.422
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
      
 0.409
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.