Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (292 aa)    
Predicted Functional Partners:
tolB
TolB protein precursor; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.713
trmL
Probable RNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide.
       0.683
mltD
Peptidoglycan N-acetylmuramoylhydrolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0741.
 
  
 0.593
comF
Competence protein F; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1040.
       0.581
mrcA
Peptidoglycan glycosyltransferase; Identified by sequence similarity; putative; ORF located using Glimmer/Blastx/COG0744.
 
   
 0.577
cpoB
Conserved hypothetical protein; Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division; Belongs to the CpoB family.
 
 
 0.535
mtgA
Peptidoglycan glycosyltransferase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.
 
   
 0.502
IMP
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
 
  
 0.473
mltA
Peptidoglycan N-acetylmuramoylhydrolase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG2821.
  
   
 0.470
mltG
Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
  
   
 0.466
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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