Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
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[Homology]
Score
nrfECytochrome C-type biogenesis transmembrane protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0477/TC:9.B.14.1.2. (381 aa)    
Predicted Functional Partners:
CV_4387
Probable cytochrome c-type biogenesis protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG1333.
 
  
 0.994
CV_0955
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx.
  
     0.774
CV_4257
Probable thioredoxin; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0526.
 
  
 0.758
hemD
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
  
 0.733
dsbE
Thioredoxin-related transmembrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0526.
 
  
 0.689
CV_4235
Probable (S)-2-hydroxy-acid oxidase; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG0247.
 
  
 0.675
CV_1895
Probable thioredoxin-disulfide reductase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0526.
 
  
 0.673
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.670
cyc
Cytochrome-c oxidase; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG2863.
     
 0.634
cobA2
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.611
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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