Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
macAABC export system, membrane fusion protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0845/TC:8.A.1.1.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (404 aa)    
Predicted Functional Partners:
CV_4396
Probable ABC transporter, permease protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0577.
 
  
 0.976
macB
Probable ABC transporter, ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
 
  
 0.960
CV_4397
Probable ABC transporter, ATP-binding protein; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1136.
 
  
 0.951
CV_4400
Probable colicin V secretion ABC transporter ATP-binding protein; Identified by sequence similarity; putative; ORF located using Blastx/COG2274.
  
 
 0.893
natC
Periplasmic type I secretion system; Identified by sequence similarity; putative; ORF located using Glimmer/GeneMark/Blastx/COG1538/TC:1.B.17.1.1.
 
 0.841
CV_4399
Hypothetical protein.
       0.796
CV_0308
Probable agglutination protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1538.
  
 0.754
CV_1734
Probable outer membrane protein; Identified by sequence similarity; putative; ORF located using Blastx/COG1538/TC:1.B.17.2.1.
  
 0.754
CV_0466
Conserved hypothetical protein; Identified by sequence similarity; putative; ORF located using Blastx/COG0845; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
  0.686
nolF
NolF secretion protein; Identified by sequence similarity; putative; ORF located using GeneMark/Blastx/COG0845/TC:8.A.1.2.1; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
  
0.679
Your Current Organism:
Chromobacterium violaceum
NCBI taxonomy Id: 243365
Other names: C. violaceum ATCC 12472, Chromobacterium violaceum ATCC 12472, Chromobacterium violaceum ATCC12472, Chromobacterium violaceum str. ATCC 12472
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