Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
KLO41262.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)    
Predicted Functional Partners:
menD
2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate synthase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily.
 
     0.860
KLO41198.1
Bromoperoxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.826
KLO41200.1
GDP-mannose-dependent alpha-mannosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.778
KLO46137.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO43402.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO42121.1
Peptidase M50; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO40236.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO39891.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO36245.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
KLO33919.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.774
Your Current Organism:
Mycobacterium nebraskense
NCBI taxonomy Id: 244292
Other names: ATCC BAA-837, DSM 44803, M. nebraskense, Mycobacterium nebraskense Mohamed et al. 2004, Mycobacterium nebraskiae, Mycobacterium sp. UNMC-MY1349
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