node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ENSCSEP00000024087 | LOC103376735 | ENSCSEP00000024087 | ENSCSEP00000000939 | Dehydrogenase E1 and transketolase domain containing 1. | Dihydrolipoamide S-succinyltransferase. | 0.960 |
ENSCSEP00000024087 | LOC103387225 | ENSCSEP00000024087 | ENSCSEP00000007285 | Dehydrogenase E1 and transketolase domain containing 1. | Oxoglutarate dehydrogenase like. | 0.561 |
ENSCSEP00000024087 | LOC103389654 | ENSCSEP00000024087 | ENSCSEP00000013142 | Dehydrogenase E1 and transketolase domain containing 1. | Transket_pyr domain-containing protein. | 0.577 |
ENSCSEP00000024087 | OGDH | ENSCSEP00000024087 | ENSCSEP00000014033 | Dehydrogenase E1 and transketolase domain containing 1. | Oxoglutarate dehydrogenase. | 0.575 |
ENSCSEP00000024087 | bckdha | ENSCSEP00000024087 | ENSCSEP00000011178 | Dehydrogenase E1 and transketolase domain containing 1. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.763 |
ENSCSEP00000024087 | dld | ENSCSEP00000024087 | ENSCSEP00000002445 | Dehydrogenase E1 and transketolase domain containing 1. | Dihydrolipoyl dehydrogenase. | 0.944 |
ENSCSEP00000024087 | pdhb | ENSCSEP00000024087 | ENSCSEP00000029021 | Dehydrogenase E1 and transketolase domain containing 1. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.783 |
ENSCSEP00000024087 | sucla2 | ENSCSEP00000024087 | ENSCSEP00000032326 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.748 |
ENSCSEP00000024087 | suclg1 | ENSCSEP00000024087 | ENSCSEP00000014566 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.912 |
ENSCSEP00000024087 | suclg2 | ENSCSEP00000024087 | ENSCSEP00000008537 | Dehydrogenase E1 and transketolase domain containing 1. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.748 |
LOC103376735 | ENSCSEP00000024087 | ENSCSEP00000000939 | ENSCSEP00000024087 | Dihydrolipoamide S-succinyltransferase. | Dehydrogenase E1 and transketolase domain containing 1. | 0.960 |
LOC103376735 | LOC103387225 | ENSCSEP00000000939 | ENSCSEP00000007285 | Dihydrolipoamide S-succinyltransferase. | Oxoglutarate dehydrogenase like. | 0.995 |
LOC103376735 | LOC103389654 | ENSCSEP00000000939 | ENSCSEP00000013142 | Dihydrolipoamide S-succinyltransferase. | Transket_pyr domain-containing protein. | 0.995 |
LOC103376735 | OGDH | ENSCSEP00000000939 | ENSCSEP00000014033 | Dihydrolipoamide S-succinyltransferase. | Oxoglutarate dehydrogenase. | 0.995 |
LOC103376735 | bckdha | ENSCSEP00000000939 | ENSCSEP00000011178 | Dihydrolipoamide S-succinyltransferase. | 2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). | 0.958 |
LOC103376735 | dld | ENSCSEP00000000939 | ENSCSEP00000002445 | Dihydrolipoamide S-succinyltransferase. | Dihydrolipoyl dehydrogenase. | 0.999 |
LOC103376735 | pdhb | ENSCSEP00000000939 | ENSCSEP00000029021 | Dihydrolipoamide S-succinyltransferase. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.964 |
LOC103376735 | sucla2 | ENSCSEP00000000939 | ENSCSEP00000032326 | Dihydrolipoamide S-succinyltransferase. | Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.984 |
LOC103376735 | suclg1 | ENSCSEP00000000939 | ENSCSEP00000014566 | Dihydrolipoamide S-succinyltransferase. | Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. | 0.991 |
LOC103376735 | suclg2 | ENSCSEP00000000939 | ENSCSEP00000008537 | Dihydrolipoamide S-succinyltransferase. | Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.974 |