STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSCSEP00000020022SERPIN domain-containing protein; Belongs to the serpin family. (370 aa)    
Predicted Functional Partners:
LOC103389837
Coagulation factor II (thrombin); Belongs to the peptidase S1 family.
   
 0.775
vtn
Vitronectin a.
   
 0.523
LOC103395458
Vitronectin b.
   
 0.523
LOC103389608
Fibrinogen alpha chain.
   
 0.499
fgb
Fibrinogen beta chain.
   
 0.489
ENSCSEP00000001081
Uncharacterized protein.
   
 
  0.477
plg
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
   
 0.465
fgg
Fibrinogen gamma chain.
   
 0.438
LOC103396845
Uncharacterized protein.
   
 0.433
ENSCSEP00000004267
Cathepsin L.1; Belongs to the peptidase C1 family.
    
 0.419
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.