STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rabgef1RAB guanine nucleotide exchange factor (GEF) 1. (498 aa)    
Predicted Functional Partners:
rabep1
Rabaptin, RAB GTPase binding effector protein 1.
   
 0.999
rabep2
Rabaptin, RAB GTPase binding effector protein 2.
   
 0.999
als2
Alsin Rho guanine nucleotide exchange factor ALS2 b.
    
 0.965
GGA1
Golgi associated, gamma adaptin ear containing, ARF binding protein 1.
    
 0.965
ENSCSEP00000017667
Uncharacterized protein.
    
 0.965
LOC103392298
PH domain-containing protein.
    
 0.965
LOC103395739
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
     
 0.958
rab21
RAB21, member RAS oncogene family.
   
 0.954
LOC103391561
RAB5B, member RAS oncogene family.
   
 0.939
LOC103388351
RAB5A, member RAS oncogene family, b.
   
 0.939
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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