STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uhrf1Ubiquitin-like with PHD and ring finger domains 1. (803 aa)    
Predicted Functional Partners:
dnmt1
DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
  
 0.960
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
    
 
 0.830
ENSCSEP00000033782
DNA ligase.
   
 
 0.765
pcna
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
   0.734
LOC103385171
DNA (cytosine-5-)-methyltransferase beta, duplicate b.3; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
   
 0.606
usp40
Ubiquitin specific peptidase 40; Belongs to the peptidase C19 family.
    
 
 0.598
sumo1
Small ubiquitin-related modifier.
    
 0.576
ENSCSEP00000026706
Ubiquilin 4.
    
 0.540
ENSCSEP00000033616
DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a.
   
 
 0.531
LOC103382849
Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes.
   
 
 0.514
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.