STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metMET proto-oncogene, receptor tyrosine kinase. (1420 aa)    
Predicted Functional Partners:
gab1
GRB2-associated binding protein 1.
    
 0.991
hgf
Hepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.966
LOC103382777
Hepatocyte growth factor a; Belongs to the peptidase S1 family. Plasminogen subfamily.
    
 0.966
lrig1
Leucine-rich repeats and immunoglobulin-like domains 1.
    
 0.958
lrig3
Leucine-rich repeats and immunoglobulin-like domains 3.
    
 0.957
lrig2
Leucine-rich repeats and immunoglobulin-like domains 2.
    
 0.957
LOC103384639
Tensin 2a.
   
 0.955
TNS3
Tensin 3.
   
 0.955
ENSCSEP00000007540
Phosphatase tensin-type domain-containing protein.
   
 0.955
Tns2
Tensin 2b.
   
 0.955
Your Current Organism:
Cynoglossus semilaevis
NCBI taxonomy Id: 244447
Other names: C. semilaevis, Cynoglossus (Arelia) semilaevis, half-smooth tongue sole, tongue sole
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