STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rumA23S rRNA (uracil-5-)-methyltransferase RumA; Identified by match to protein family HMM PF05958; match to protein family HMM TIGR00479; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (441 aa)    
Predicted Functional Partners:
maf
Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
     0.906
whiA
Conserved hypothetical protein; Involved in cell division and chromosome segregation.
     
 0.875
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
  
  
 0.875
CHY_1233
Identified by match to protein family HMM PF02219; Belongs to the methylenetetrahydrofolate reductase family.
     
 0.752
CHY_1110
Nucleotidyltransferase substrate binding protein, HI0074 family; Identified by match to protein family HMM TIGR01987.
       0.701
CHY_1111
Nucleotidyltransferase domain protein; Identified by similarity to GB:AAM25166.1; match to protein family HMM PF01909.
       0.701
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
 
   
 0.670
CHY_2029
NOL1/NOP2/sun family protein; Identified by similarity to GB:AAM25312.1; match to protein family HMM PF01189; match to protein family HMM TIGR00446.
 
  
 0.636
CHY_1949
Identified by match to protein family HMM PF00571; match to protein family HMM PF01368; match to protein family HMM PF01743; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.558
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.528
Your Current Organism:
Carboxydothermus hydrogenoformans
NCBI taxonomy Id: 246194
Other names: C. hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans Z-2901, Carboxydothermus hydrogenoformans str. Z-2901
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