node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHY_0525 | CHY_0572 | CHY_0525 | CHY_0572 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Identified by match to protein family HMM PF00501. | 0.917 |
CHY_0525 | acoE | CHY_0525 | CHY_0659 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.917 |
CHY_0525 | acsA | CHY_0525 | CHY_0249 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.917 |
CHY_0525 | leuA | CHY_0525 | CHY_0521 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.985 |
CHY_0525 | mhpF | CHY_0525 | CHY_1279 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.981 |
CHY_0525 | nifV | CHY_0525 | CHY_1104 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Homocitrate synthase; Identified by similarity to SP:Q44290; match to protein family HMM PF00682; match to protein family HMM TIGR02660; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.923 |
CHY_0525 | pta | CHY_0525 | CHY_1456 | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Phosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651. | 0.905 |
CHY_0572 | CHY_0525 | CHY_0572 | CHY_0525 | Identified by match to protein family HMM PF00501. | Putative (R)-citramalate synthase; Identified by similarity to SP:Q58787; match to protein family HMM PF00682; match to protein family HMM TIGR00977; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.917 |
CHY_0572 | acoE | CHY_0572 | CHY_0659 | Identified by match to protein family HMM PF00501. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.918 |
CHY_0572 | acsA | CHY_0572 | CHY_0249 | Identified by match to protein family HMM PF00501. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.918 |
CHY_0572 | leuA | CHY_0572 | CHY_0521 | Identified by match to protein family HMM PF00501. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.917 |
CHY_0572 | mhpF | CHY_0572 | CHY_1279 | Identified by match to protein family HMM PF00501. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.905 |
CHY_0572 | nifV | CHY_0572 | CHY_1104 | Identified by match to protein family HMM PF00501. | Homocitrate synthase; Identified by similarity to SP:Q44290; match to protein family HMM PF00682; match to protein family HMM TIGR02660; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.917 |
CHY_0572 | pta | CHY_0572 | CHY_1456 | Identified by match to protein family HMM PF00501. | Phosphate acetyltransferase; Identified by similarity to SP:P39646; match to protein family HMM PF01515; match to protein family HMM TIGR00651. | 0.921 |
CHY_1278 | CHY_1322 | CHY_1278 | CHY_1322 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Identified by match to protein family HMM PF01689. | 0.900 |
CHY_1278 | mhpE | CHY_1278 | CHY_1280 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.993 |
CHY_1278 | mhpF | CHY_1278 | CHY_1279 | Identified by similarity to GP:45682; match to protein family HMM PF01689. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.976 |
CHY_1322 | CHY_1278 | CHY_1322 | CHY_1278 | Identified by match to protein family HMM PF01689. | Identified by similarity to GP:45682; match to protein family HMM PF01689. | 0.900 |
CHY_1322 | mhpE | CHY_1322 | CHY_1280 | Identified by match to protein family HMM PF01689. | 4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. | 0.982 |
CHY_1322 | mhpF | CHY_1322 | CHY_1279 | Identified by match to protein family HMM PF01689. | Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. | 0.934 |