node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CHY_2369 | CHY_2378 | CHY_2369 | CHY_2378 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | 0.698 |
CHY_2369 | birA | CHY_2369 | CHY_2371 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.865 |
CHY_2369 | coaX | CHY_2369 | CHY_2370 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Puatative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.854 |
CHY_2369 | nadB | CHY_2369 | CHY_2373 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.808 |
CHY_2369 | nadC | CHY_2369 | CHY_2372 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family. | 0.837 |
CHY_2369 | panB | CHY_2369 | CHY_2377 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.685 |
CHY_2369 | panC | CHY_2369 | CHY_2376 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.891 |
CHY_2369 | panD | CHY_2369 | CHY_2375 | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.765 |
CHY_2378 | CHY_2369 | CHY_2378 | CHY_2369 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.698 |
CHY_2378 | birA | CHY_2378 | CHY_2371 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.808 |
CHY_2378 | coaX | CHY_2378 | CHY_2370 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | Puatative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.796 |
CHY_2378 | nadB | CHY_2378 | CHY_2373 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. | 0.746 |
CHY_2378 | nadC | CHY_2378 | CHY_2372 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078; Belongs to the NadC/ModD family. | 0.730 |
CHY_2378 | panB | CHY_2378 | CHY_2377 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.928 |
CHY_2378 | panC | CHY_2378 | CHY_2376 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.991 |
CHY_2378 | panD | CHY_2378 | CHY_2375 | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.853 |
birA | CHY_2369 | CHY_2371 | CHY_2369 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative TIM-barrel protein, NifR3 family; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. | 0.865 |
birA | CHY_2378 | CHY_2371 | CHY_2378 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Conserved hypothetical protein; Identified by similarity to GB:AAO81619.1; match to protein family HMM PF01210; match to protein family HMM PF03807. | 0.808 |
birA | cmk | CHY_2371 | CHY_1927 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. | 0.431 |
birA | coaBC | CHY_2371 | CHY_1486 | BirA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.461 |