sbcC protein (Dichelobacter nodosus) - STRING interaction network

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Score

sbcC

Exonuclease SbcC; Identified by match to protein family HMM PF02463. (988 aa)

Predicted Functional Partners:

sbcD

0.997

DNO_0249

0.885

polA

0.883

DNO_0364

0.773

DNO_0367

0.773

topA

0.717

frr

0.709

recA

0.693

DNO_0572

0.533

recD

0.527

Your Current Organism:

Dichelobacter nodosus

NCBI taxonomy Id: 246195
Other names: D. nodosus VCS1703A, Dichelobacter nodosus VCS1703A, Dichelobacter nodosus str. VCS1703A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DNO_0249	DNO_0572	DNO_0249	DNO_0572	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	Helicase domain protein.	0.506
DNO_0249	polA	DNO_0249	DNO_0206	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.893
DNO_0249	recA	DNO_0249	DNO_0288	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.562
DNO_0249	recD	DNO_0249	DNO_0408	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	Exonuclease V, alpha subunit; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Ho [...]	0.402
DNO_0249	sbcC	DNO_0249	DNO_0366	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	Exonuclease SbcC; Identified by match to protein family HMM PF02463.	0.885
DNO_0249	topA	DNO_0249	DNO_0152	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.428
DNO_0364	DNO_0367	DNO_0364	DNO_0367	ABC transporter domain protein; Identified by match to protein family HMM PF00005.	Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.	0.773
DNO_0364	sbcC	DNO_0364	DNO_0366	ABC transporter domain protein; Identified by match to protein family HMM PF00005.	Exonuclease SbcC; Identified by match to protein family HMM PF02463.	0.773
DNO_0364	sbcD	DNO_0364	DNO_0365	ABC transporter domain protein; Identified by match to protein family HMM PF00005.	Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.778
DNO_0367	DNO_0364	DNO_0367	DNO_0364	Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.	ABC transporter domain protein; Identified by match to protein family HMM PF00005.	0.773
DNO_0367	sbcC	DNO_0367	DNO_0366	Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.	Exonuclease SbcC; Identified by match to protein family HMM PF02463.	0.773
DNO_0367	sbcD	DNO_0367	DNO_0365	Identified by match to protein family HMM PF00107; match to protein family HMM PF08240.	Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.773
DNO_0572	DNO_0249	DNO_0572	DNO_0249	Helicase domain protein.	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	0.506
DNO_0572	polA	DNO_0572	DNO_0206	Helicase domain protein.	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	0.838
DNO_0572	recA	DNO_0572	DNO_0288	Helicase domain protein.	DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.	0.533
DNO_0572	sbcC	DNO_0572	DNO_0366	Helicase domain protein.	Exonuclease SbcC; Identified by match to protein family HMM PF02463.	0.533
DNO_0572	sbcD	DNO_0572	DNO_0365	Helicase domain protein.	Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family.	0.587
DNO_0572	topA	DNO_0572	DNO_0152	Helicase domain protein.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.491
frr	sbcC	DNO_0720	DNO_0366	Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family.	Exonuclease SbcC; Identified by match to protein family HMM PF02463.	0.709
polA	DNO_0249	DNO_0206	DNO_0249	DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.	Conserved hypothetical protein; Identified by match to protein family HMM PF00149.	0.893