node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DNO_0249 | DNO_0572 | DNO_0249 | DNO_0572 | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | Helicase domain protein. | 0.648 |
DNO_0249 | polA | DNO_0249 | DNO_0206 | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.962 |
DNO_0249 | recA | DNO_0249 | DNO_0288 | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.564 |
DNO_0249 | sbcC | DNO_0249 | DNO_0366 | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | Exonuclease SbcC; Identified by match to protein family HMM PF02463. | 0.962 |
DNO_0249 | topA | DNO_0249 | DNO_0152 | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.651 |
DNO_0363 | DNO_0364 | DNO_0363 | DNO_0364 | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | 0.598 |
DNO_0363 | DNO_0367 | DNO_0363 | DNO_0367 | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | 0.526 |
DNO_0363 | sbcC | DNO_0363 | DNO_0366 | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Exonuclease SbcC; Identified by match to protein family HMM PF02463. | 0.526 |
DNO_0363 | sbcD | DNO_0363 | DNO_0365 | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.530 |
DNO_0364 | DNO_0363 | DNO_0364 | DNO_0363 | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.598 |
DNO_0364 | DNO_0367 | DNO_0364 | DNO_0367 | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | 0.774 |
DNO_0364 | sbcC | DNO_0364 | DNO_0366 | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | Exonuclease SbcC; Identified by match to protein family HMM PF02463. | 0.773 |
DNO_0364 | sbcD | DNO_0364 | DNO_0365 | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.776 |
DNO_0367 | DNO_0363 | DNO_0367 | DNO_0363 | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | Septum formation initiator family protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. | 0.526 |
DNO_0367 | DNO_0364 | DNO_0367 | DNO_0364 | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | ABC transporter domain protein; Identified by match to protein family HMM PF00005. | 0.774 |
DNO_0367 | sbcC | DNO_0367 | DNO_0366 | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | Exonuclease SbcC; Identified by match to protein family HMM PF02463. | 0.773 |
DNO_0367 | sbcD | DNO_0367 | DNO_0365 | Identified by match to protein family HMM PF00107; match to protein family HMM PF08240. | Exonuclease SbcD; SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'->5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity; Belongs to the SbcD family. | 0.773 |
DNO_0572 | DNO_0249 | DNO_0572 | DNO_0249 | Helicase domain protein. | Conserved hypothetical protein; Identified by match to protein family HMM PF00149. | 0.648 |
DNO_0572 | polA | DNO_0572 | DNO_0206 | Helicase domain protein. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.922 |
DNO_0572 | recA | DNO_0572 | DNO_0288 | Helicase domain protein. | DNA recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.572 |