ABK70762.1 protein (Mycolicibacterium smegmatis)

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Score

ABK70762.1

Ppe family protein; Identified by match to protein family HMM PF00823. (431 aa)

Predicted Functional Partners:

esxB

0.891

espG1

0.859

esxA

0.817

PE35

0.735

ABK75780.1

0.724

ABK71164.1

0.724

espE

0.656

ABK74495.1

0.617

pE

0.541

eccCb1

0.536

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70762.1	ABK71164.1	MSMEG_0064	MSMEG_0723	Ppe family protein; Identified by match to protein family HMM PF00823.	Conserved hypothetical protein.	0.724
ABK70762.1	ABK74495.1	MSMEG_0064	MSMEG_0061	Ppe family protein; Identified by match to protein family HMM PF00823.	Identified by match to protein family HMM PF01580.	0.617
ABK70762.1	ABK75780.1	MSMEG_0064	MSMEG_0078	Ppe family protein; Identified by match to protein family HMM PF00823.	Hypothetical protein; Identified by Glimmer2; putative.	0.724
ABK70762.1	PE35	MSMEG_0064	MSMEG_0063	Ppe family protein; Identified by match to protein family HMM PF00823.	PE family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB (Probable). Plays a role in DNA conjugation, in at least a donor strain.	0.735
ABK70762.1	eccCb1	MSMEG_0064	MSMEG_0062	Ppe family protein; Identified by match to protein family HMM PF00823.	Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains.	0.536
ABK70762.1	espE	MSMEG_0064	MSMEG_0055	Ppe family protein; Identified by match to protein family HMM PF00823.	Hypothetical protein; Identified by Glimmer2; putative.	0.656
ABK70762.1	espG1	MSMEG_0064	MSMEG_0057	Ppe family protein; Identified by match to protein family HMM PF00823.	Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Specific chaperone for cognate PE/PPE proteins, plays an important role in preventing aggregation of PE/PPE dimers (By similarity). Also plays a role in DNA conjugation, in at least recipient strain (By similarity). ECO:0000250\|UniProtKB:L8FPI5, ; Belongs to the EspG family.	0.859
ABK70762.1	esxA	MSMEG_0064	MSMEG_0066	Ppe family protein; Identified by match to protein family HMM PF00823.	Early secretory antigenic target, 6 kDa; An exported protein. Unlike its M.tuberculosis counterpart has poor pore forming ability in artificial liposomes, does not undergo conformational change at acidic pH. Mutation of 2 residues to those found in M.tuberculosis (25-TA-26 to IH) alters the properties of this protein so that it inserts into liposomes at acidic pH, forming pores, like its M.tuberculosis counterpart.	0.817
ABK70762.1	esxB	MSMEG_0064	MSMEG_0065	Ppe family protein; Identified by match to protein family HMM PF00823.	Conserved hypothetical protein; An exported protein. Plays a role in DNA conjugation, in at least a donor strain ; Belongs to the WXG100 family. CFP-10 subfamily.	0.891
ABK70762.1	pE	MSMEG_0064	MSMEG_0412	Ppe family protein; Identified by match to protein family HMM PF00823.	Conserved hypothetical protein.	0.541
ABK71164.1	ABK70762.1	MSMEG_0723	MSMEG_0064	Conserved hypothetical protein.	Ppe family protein; Identified by match to protein family HMM PF00823.	0.724
ABK71164.1	ABK74495.1	MSMEG_0723	MSMEG_0061	Conserved hypothetical protein.	Identified by match to protein family HMM PF01580.	0.425
ABK71164.1	espG1	MSMEG_0723	MSMEG_0057	Conserved hypothetical protein.	Conserved hypothetical protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Specific chaperone for cognate PE/PPE proteins, plays an important role in preventing aggregation of PE/PPE dimers (By similarity). Also plays a role in DNA conjugation, in at least recipient strain (By similarity). ECO:0000250\|UniProtKB:L8FPI5, ; Belongs to the EspG family.	0.704
ABK71164.1	esxA	MSMEG_0723	MSMEG_0066	Conserved hypothetical protein.	Early secretory antigenic target, 6 kDa; An exported protein. Unlike its M.tuberculosis counterpart has poor pore forming ability in artificial liposomes, does not undergo conformational change at acidic pH. Mutation of 2 residues to those found in M.tuberculosis (25-TA-26 to IH) alters the properties of this protein so that it inserts into liposomes at acidic pH, forming pores, like its M.tuberculosis counterpart.	0.507
ABK71164.1	esxB	MSMEG_0723	MSMEG_0065	Conserved hypothetical protein.	Conserved hypothetical protein; An exported protein. Plays a role in DNA conjugation, in at least a donor strain ; Belongs to the WXG100 family. CFP-10 subfamily.	0.510
ABK74495.1	ABK70762.1	MSMEG_0061	MSMEG_0064	Identified by match to protein family HMM PF01580.	Ppe family protein; Identified by match to protein family HMM PF00823.	0.617
ABK74495.1	ABK71164.1	MSMEG_0061	MSMEG_0723	Identified by match to protein family HMM PF01580.	Conserved hypothetical protein.	0.425
ABK74495.1	ABK75780.1	MSMEG_0061	MSMEG_0078	Identified by match to protein family HMM PF01580.	Hypothetical protein; Identified by Glimmer2; putative.	0.425
ABK74495.1	PE35	MSMEG_0061	MSMEG_0063	Identified by match to protein family HMM PF01580.	PE family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB (Probable). Plays a role in DNA conjugation, in at least a donor strain.	0.776
ABK74495.1	eccCb1	MSMEG_0061	MSMEG_0062	Identified by match to protein family HMM PF01580.	Ftsk/spoiiie family protein; Part of the ESX-1 / type VII specialized secretion system (T7SS), which exports several proteins including EsxA and EsxB. Plays a role in DNA conjugation, in both donor and recipient strains.	0.988