Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72576.1NAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (477 aa)    
Predicted Functional Partners:
ABK71348.1
Alanine dehydrogenase/pyridine nucleotide transhydrogenase; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
 0.999
ABK74118.1
PntAB protein.
 
 0.998
pntA
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
 0.996
pntA-2
NAD(P) transhydrogenase, alpha subunit; Identified by similarity to SP:P07001; match to protein family HMM PF01262; match to protein family HMM PF05222; match to protein family HMM TIGR00561.
 0.996
ABK73135.1
Identified by match to protein family HMM PF01964.
     
 0.958
ABK74591.1
oxalyl-CoA decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; Belongs to the TPP enzyme family.
   
  
 0.828
ABK69733.1
NAD-dependent formate dehydrogenase delta subunit.
   
  
 0.827
nadK
Inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NADkinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
     
 0.827
ald
Alanine dehydrogenase; Catalyzes the reversible reductive amination of pyruvate to L-alanine. May be required for the adaptation from aerobic growth to anaerobic dormancy. I could be involved in the maintenance of the NAD pool during the shift to an anaerobic dormant state in which oxygen as a terminal electron acceptor becomes limited.
   
  0.720
nadE
Glutamine-dependent NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
     
 0.700
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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