Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74877.1Integral membrane transport protein; Identified by match to protein family HMM PF00474; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (519 aa)    
Predicted Functional Partners:
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
     0.826
ABK75724.1
Identified by match to protein family HMM PF01869.
 
     0.826
ABK70568.1
Acetyltransferase; Identified by match to protein family HMM PF00583.
     
 0.746
ABK70356.1
Beta-lactamase; Identified by match to protein family HMM PF00144.
     0.692
murQ
Putative glucokinase regulator; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate.
 
     0.631
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
  
 0.600
ABK75795.1
Two-component system sensor kinase; Identified by match to protein family HMM PF00989; match to protein family HMM PF01590; match to protein family HMM PF02518; match to protein family HMM PF07730; match to protein family HMM TIGR00229.
  
 
 0.542
ABK69979.1
Proline dehydrogenase; Identified by match to protein family HMM PF01619.
  
  
 0.515
ABK71143.1
Two-component system sensor kinase; Identified by match to protein family HMM PF02518; match to protein family HMM PF07730; match to protein family HMM TIGR00229.
  
 
 0.498
ABK75578.1
Transcriptional regulator, RpiR family protein; Identified by match to protein family HMM PF01380; match to protein family HMM PF01418.
       0.492
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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