ABK74387.1 protein (Mycolicibacterium smegmatis)

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Score

ABK74387.1

ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (787 aa)

Predicted Functional Partners:

uvrB

0.974

ABK75158.1

0.838

ABK75155.1

0.796

ABK75388.1

0.753

ABK70417.1

0.748

mfd

0.697

uvrC

0.696

pcrA

0.626

recA

0.625

ABK74084.1

0.610

Your Current Organism:

Mycolicibacterium smegmatis

NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABK70417.1	ABK74387.1	MSMEG_0215	MSMEG_0211	Identified by match to protein family HMM PF02678; Belongs to the pirin family.	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	0.748
ABK70417.1	ABK75155.1	MSMEG_0215	MSMEG_0213	Identified by match to protein family HMM PF02678; Belongs to the pirin family.	Transcriptional regulator; Identified by match to protein family HMM PF00165.	0.749
ABK70417.1	ABK75158.1	MSMEG_0215	MSMEG_0212	Identified by match to protein family HMM PF02678; Belongs to the pirin family.	Lyase; Identified by match to protein family HMM PF00903.	0.753
ABK70417.1	ABK75388.1	MSMEG_0215	MSMEG_0214	Identified by match to protein family HMM PF02678; Belongs to the pirin family.	L-sorbosone dehydrogenase.	0.851
ABK74084.1	ABK74387.1	MSMEG_4259	MSMEG_0211	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	0.610
ABK74084.1	mfd	MSMEG_4259	MSMEG_5423	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.727
ABK74084.1	pcrA	MSMEG_4259	MSMEG_5534	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073.	0.717
ABK74084.1	recA	MSMEG_4259	MSMEG_2723	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]	0.625
ABK74084.1	uvrB	MSMEG_4259	MSMEG_3816	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.964
ABK74084.1	uvrC	MSMEG_4259	MSMEG_3078	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.720
ABK74387.1	ABK70417.1	MSMEG_0211	MSMEG_0215	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Identified by match to protein family HMM PF02678; Belongs to the pirin family.	0.748
ABK74387.1	ABK74084.1	MSMEG_0211	MSMEG_4259	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM TIGR00573.	0.610
ABK74387.1	ABK75155.1	MSMEG_0211	MSMEG_0213	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Transcriptional regulator; Identified by match to protein family HMM PF00165.	0.796
ABK74387.1	ABK75158.1	MSMEG_0211	MSMEG_0212	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Lyase; Identified by match to protein family HMM PF00903.	0.838
ABK74387.1	ABK75388.1	MSMEG_0211	MSMEG_0214	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	L-sorbosone dehydrogenase.	0.753
ABK74387.1	mfd	MSMEG_0211	MSMEG_5423	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily.	0.697
ABK74387.1	pcrA	MSMEG_0211	MSMEG_5534	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	ATP-dependent DNA helicase PcrA; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR01073.	0.626
ABK74387.1	recA	MSMEG_0211	MSMEG_2723	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Protein RecA; Required for homologous recombination (HR) and the bypass of mutagenic DNA lesions (double strand breaks, DSB) by the SOS response. Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. Numerous X-ray crystals have been resolved under different conditions which indicate the flexibility of the protein, essential to its function. Gln-196 contributes to this plasticity by acting as a switch residue, which transmits the ef [...]	0.625
ABK74387.1	uvrB	MSMEG_0211	MSMEG_3816	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]	0.974
ABK74387.1	uvrC	MSMEG_0211	MSMEG_3078	ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005.	Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.	0.696