Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75263.1RNA polymerase sigma-70 factor, family protein; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; match to protein family HMM TIGR02960; Belongs to the sigma-70 factor family. ECF subfamily. (340 aa)    
Predicted Functional Partners:
ABK74423.1
Monoglyceride lipase; Involved in the hydrolysis of exogenous host. Catalyzes the hydrolysis of long-chain monoacylglycerol. It hydrolyzes monoolein and monoacylglycerols (MAG) with fatty acid chains ranging from C14 to C18, but is unable to hydrolyze long-chain diacylglycerol (DAG).
     
 0.585
ABK74753.1
Secreted protein.
     
 0.566
ABK74691.1
Conserved hypothetical protein.
 
  
 0.516
ABK71473.1
O-methyltransferase MdmC; Identified by match to protein family HMM PF01135; match to protein family HMM PF01596.
       0.496
ABK72359.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. ECF subfamily.
 
   
 0.494
ABK74419.1
Conserved hypothetical protein.
  
 
 0.478
rshA
Anti-sigma factor, family protein; A redox-regulated anti-sigma factor for cognate extracytoplasmic function (ECF) sigma factor SigH. ECF sigma factors are held in an inactive form by an anti-sigma factor (Probable). Overexpression leads to increased susceptibility to diamide.
  
 
 0.478
ABK73105.1
Conserved hypothetical protein.
       0.471
ABK73301.1
Conserved hypothetical protein.
       0.470
trxB
Thioredoxin-disulfide reductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992; match to protein family HMM TIGR01292.
     
 0.468
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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