Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK74706.1Glycolate oxidase subunit; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913. (622 aa)    
Predicted Functional Partners:
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 
 0.952
ABK74357.1
Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
  
  
 
0.947
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.946
ABK73728.1
5'-nucleotidase; Identified by match to protein family HMM PF00702; match to protein family HMM TIGR01549.
    
 0.940
aceA
Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.
     
 0.938
aceA-2
Isocitrate lyase; Identified by match to protein family HMM PF00463; match to protein family HMM TIGR01346.
     
 0.938
eda
2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase; Identified by similarity to SP:P10177; match to protein family HMM PF01081; match to protein family HMM TIGR01182.
  
 
 0.857
ABK72182.1
Phosphonoacetaldehyde hydrolase; Identified by match to protein family HMM PF00702.
    
 0.854
ABK74579.1
Glyoxylate reductase; Identified by match to protein family HMM PF00389; match to protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
 
 
 0.796
ABK75134.1
Oxidoreductase, FAD-binding; Identified by match to protein family HMM PF01565; match to protein family HMM PF02913.
  
  
 
0.765
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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