Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK71089.1Putative glycosyl transferase; Identified by match to protein family HMM PF03033. (418 aa)    
Predicted Functional Partners:
ABK73314.1
Condensation domain protein; Identified by match to protein family HMM PF00668.
 
     0.735
ABK72522.1
NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.
 
 
 0.701
ABK73350.1
Condensation domain protein; Identified by match to protein family HMM PF00668.
 
   
 0.694
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
 
  
 0.668
stf0
Conserved hypothetical protein; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid in pathogenic mycobacteria. Cannot use free glucose and unnatural stereoisomers of trehalose (alpha,beta (neo-trehalose) and beta,beta (iso-trehalose)) as substrates.
  
     0.587
ABK72554.1
Conserved hypothetical protein.
  
     0.586
ABK71204.1
Rmt3 protein.
 
  
 0.558
ABK70957.1
Conserved hypothetical protein.
 
     0.543
pks5
Mycocerosic acid synthase; Polyketide synthase involved in the biosynthesis of 2,4- dimethyl-2-eicosenoic acid, a lipid component of the lipooligosaccharides (LOS) which are not located at the bacterial surface but rather in deeper compartments of the cell envelope of M.smegmatis.
 
  
 0.522
ABK75192.1
Cytochrome P450 51; Identified by match to protein family HMM PF00067; Belongs to the cytochrome P450 family.
 
 0.513
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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