Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
tylFMacrocin-O-methyltransferase; Identified by match to protein family HMM PF05711. (240 aa)    
Predicted Functional Partners:
gtf1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
 
 0.798
ABK75432.1
Putative acyltransferase; Identified by match to protein family HMM PF01757.
 
    0.668
ABK71734.1
Rmt2 protein.
 
     0.644
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
     
 0.635
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
 
 0.623
ABK70957.1
Conserved hypothetical protein.
 
  
 0.549
ABK72522.1
NAD dependent epimerase/dehydratase family protein; Identified by match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF04321; match to protein family HMM PF07993.
 
 
 0.528
ABK71204.1
Rmt3 protein.
 
   
0.496
ABK71089.1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
  
 0.484
ABK71245.1
O-acyl transferase; Identified by match to protein family HMM PF01757.
 
     0.477
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (26%) [HD]