STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ecfExtra cytoplasmic sigma factor; Identified by match to protein family HMM PF04542; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family. (391 aa)    
Predicted Functional Partners:
sap
Sigma associated protein; Identified by match to protein family HMM PF04946.
 
  
 0.972
ABK71020.1
Identified by match to protein family HMM PF04946.
 
    0.760
mbtH
Conserved domain protein; Identified by match to protein family HMM PF03621.
     
 0.728
ABK72365.1
Dgpf protein; Identified by match to protein family HMM PF04946.
 
    0.687
ABK71392.1
Putative DNA-binding protein.
  
     0.573
sigH
RNA polymerase sigma-70 factor, family protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. Extracytoplasmic function (ECF) sigma factors are held in an inactive form by an anti-sigma factor until released. This sigma factor is involved in heat shock and oxidative stress responses.
      
 0.563
gtf1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
      
 0.539
ABK74272.1
3-demethylubiquinone-9 3-methyltransferase; Identified by match to protein family HMM PF06983.
 
     0.537
mmpS4
MmpS4 protein; Identified by match to protein family HMM PF05423.
      
 0.530
gap-2
Integral membrane protein; Required for the transport of peptidoglycolipids (GPLs) to the cell surface.
       0.519
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.