Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ABK73314.1Condensation domain protein; Identified by match to protein family HMM PF00668. (473 aa)    
Predicted Functional Partners:
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
 
  
 0.974
mmpL
MmpL protein; Identified by match to protein family HMM PF03176; match to protein family HMM TIGR00833.
 
  
 0.873
fadD28
acyl-CoA synthase; Identified by match to protein family HMM PF00501.
 
  
 0.787
ABK70957.1
Conserved hypothetical protein.
 
     0.772
ABK72554.1
Conserved hypothetical protein.
  
     0.758
gtf1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
    0.754
ABK71212.1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
     0.739
ABK71089.1
Putative glycosyl transferase; Identified by match to protein family HMM PF03033.
 
     0.735
pE
Conserved hypothetical protein.
  
  
 0.730
stf0
Conserved hypothetical protein; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid in pathogenic mycobacteria. Cannot use free glucose and unnatural stereoisomers of trehalose (alpha,beta (neo-trehalose) and beta,beta (iso-trehalose)) as substrates.
  
     0.727
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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