Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK73407.1Para-nitrobenzyl esterase; Identified by match to protein family HMM PF00135; Belongs to the type-B carboxylesterase/lipase family. (534 aa)    
Predicted Functional Partners:
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
   
 0.628
ABK70355.1
Hydrolase; Identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389.
  
 0.617
ABK70886.1
Leupeptin-inactivating enzyme 1; Identified by match to protein family HMM PF01546; match to protein family HMM PF02225; match to protein family HMM PF04389.
  
 0.617
ABK70095.1
Identified by match to protein family HMM PF00570; match to protein family HMM PF01612.
    
 0.536
ABK72176.1
ATP-dependent RNA helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271.
   
 0.528
ABK71608.1
DEAD/DEAH box helicase; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family.
   
 0.528
deaD
ATP-dependent rna helicase, dead/deah box family protein; DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation.
   
 0.528
hrpA
ATP-dependent helicase HrpA; Identified by match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM PF07717; match to protein family HMM TIGR01967.
    
 0.524
ABK70407.1
Putative lipoprotein.
       0.515
rpsA
30S ribosomal protein S1; Binds mRNA, facilitating recognition of most mRNAs by the 30S ribosomal subunit during translation initiation (By similarity). Plays a role in trans-translation; binds tmRNA (the product of the ssrA gene). Binds very poorly to pyrazinoic acid (POA), the active form of the prodrug pyrazinamide (PZA); POA does not disrupt trans-translation in this organism. M.smegmatis is resistant to the antibiotic PZA. In trans-translation Ala-aminoacylated transfer-messenger RNA (tmRNA, product of the ssrA gene; the 2 termini fold to resemble tRNA(Ala) while it encodes a shor [...]
   
 
  0.494
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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