Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK72125.1FAD dependent oxidoreductase; Identified by match to protein family HMM PF01266. (448 aa)    
Predicted Functional Partners:
sdhC
Succinate dehydrogenase, cytochrome b556 subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970.
  
 0.882
ABK72215.1
Fumarate hydratase class I, anaerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.877
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 0.876
ABK71627.1
Dihydroxy-acid dehydratase; Identified by match to protein family HMM PF00920; Belongs to the IlvD/Edd family.
  
 
 0.871
ABK73179.1
Pyruvate ferredoxin/flavodoxin oxidoreductase family protein; Identified by match to protein family HMM PF01558.
  
 0.808
ABK71393.1
Succinate dehydrogenase; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384.
  
 0.806
sdhB
Succinate dehydrogenase, iron-sulfur protein; Identified by similarity to SP:P51053; match to protein family HMM TIGR00384.
  
 0.806
ABK76139.1
Pyruvate synthase; Identified by match to protein family HMM PF01855.
  
 
 0.726
ABK74832.1
Shikimate transporter; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
   
 
 0.710
ABK73463.1
Iron-sulfur binding oxidoreductase; Identified by match to protein family HMM PF00355; match to protein family HMM PF01266.
  
 0.701
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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