Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
eccC3Ftsk/spoiiie family protein; Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG. (1325 aa)    
Predicted Functional Partners:
eccB3
Conserved hypothetical protein; An ATPase (By similarity). Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG.
 
 
 0.999
snm
Secretion protein Snm4; Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG; Belongs to the EccD/Snm4 family.
 
 
 0.999
eccE3
Conserved hypothetical protein; Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG.
  
 
 0.996
eccA3
ATPase, AAA family protein; Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG. EccA3 exhibits ATPase activity and may provide energy for the export of ESX-3 substrates (By similarity).
 
  
 0.981
esxH
Low molecular weight protein antigen 7; Belongs to the WXG100 family. ESAT-6 subfamily.
  
 
 0.945
ABK70912.1
Ppe family protein; Identified by match to protein family HMM PF00823.
  
  
 0.925
espG3
Putative DNA-binding protein; Belongs to the EspG family.
  
  
 0.914
esxG
Pe family protein; Belongs to the WXG100 family. CFP-10 subfamily.
     
 0.891
ABK72989.1
Pe family protein; Identified by match to protein family HMM PF00934.
     
 0.870
ABK76063.1
Methyltransferase; Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity.
 
  
 0.867
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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