| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ABK70772.1 | ABK75774.1 | MSMEG_0698 | MSMEG_0699 | Isoniazid inductible protein IniC. | Conserved hypothetical proline rich protein. | 0.852 |
| ABK73018.1 | ABK75774.1 | MSMEG_3126 | MSMEG_0699 | SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. | Conserved hypothetical proline rich protein. | 0.851 |
| ABK73018.1 | dnaJ | MSMEG_3126 | MSMEG_0711 | SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.656 |
| ABK73018.1 | dnaJ-2 | MSMEG_3126 | MSMEG_4504 | SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.656 |
| ABK75774.1 | ABK70772.1 | MSMEG_0699 | MSMEG_0698 | Conserved hypothetical proline rich protein. | Isoniazid inductible protein IniC. | 0.852 |
| ABK75774.1 | ABK73018.1 | MSMEG_0699 | MSMEG_3126 | Conserved hypothetical proline rich protein. | SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. | 0.851 |
| ABK75774.1 | dnaJ | MSMEG_0699 | MSMEG_0711 | Conserved hypothetical proline rich protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.855 |
| ABK75774.1 | dnaJ-2 | MSMEG_0699 | MSMEG_4504 | Conserved hypothetical proline rich protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.855 |
| ABK75774.1 | groL | MSMEG_0699 | MSMEG_0880 | Conserved hypothetical proline rich protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.796 |
| ABK75774.1 | groL-2 | MSMEG_0699 | MSMEG_1583 | Conserved hypothetical proline rich protein. | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.796 |
| ABK75774.1 | groL-3 | MSMEG_0699 | MSMEG_1978 | Conserved hypothetical proline rich protein. | Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family. | 0.796 |
| ABK75774.1 | groS | MSMEG_0699 | MSMEG_1582 | Conserved hypothetical proline rich protein. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.786 |
| ABK75774.1 | grpE | MSMEG_0699 | MSMEG_0710 | Conserved hypothetical proline rich protein. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.914 |
| ABK75774.1 | sucA | MSMEG_0699 | MSMEG_5049 | Conserved hypothetical proline rich protein. | 2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...] | 0.860 |
| dnaJ | ABK73018.1 | MSMEG_0711 | MSMEG_3126 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | SUF system FeS assembly protein, NifU family protein; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. | 0.656 |
| dnaJ | ABK75774.1 | MSMEG_0711 | MSMEG_0699 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Conserved hypothetical proline rich protein. | 0.855 |
| dnaJ | groL | MSMEG_0711 | MSMEG_0880 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.931 |
| dnaJ | groL-2 | MSMEG_0711 | MSMEG_1583 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.936 |
| dnaJ | groL-3 | MSMEG_0711 | MSMEG_1978 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroL; Plays an essential role in the productive folding of MimA and MimC, and thus in the formation of the active MimABCD complex. Belongs to the chaperonin (HSP60) family. | 0.848 |
| dnaJ | groS | MSMEG_0711 | MSMEG_1582 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.866 |
