Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK73846.1Transcriptional regulator, LysR family protein; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family. (317 aa)    
Predicted Functional Partners:
ABK72927.1
Transcriptional regulator; Identified by match to protein family HMM PF00126; Belongs to the LysR transcriptional regulatory family.
  
     0.768
ABK70623.1
Transcriptional regulator; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
    0.699
ABK72966.1
Transcriptional regulator, LysR family protein; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.697
ABK72951.1
4-carboxy-4-hydroxy-2-oxoadipate aldolase; Identified by match to protein family HMM PF03737.
 
     0.598
ABK73992.1
Conserved hypothetical protein; Identified by similarity to GB:CAD18384.1; match to protein family HMM PF03737.
 
     0.591
ABK72885.1
LysR-family protein transcriptional regulator; Identified by match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.539
ABK70248.1
Putative permease of the major facilitator superfamily protein; Identified by match to protein family HMM PF00083; match to protein family HMM PF07690.
  
  
 0.530
ABK72546.1
Transcriptional regulator, LysR family protein; Identified by similarity to SP:P32064; match to protein family HMM PF00126; match to protein family HMM PF03466; Belongs to the LysR transcriptional regulatory family.
  
     0.523
grpE
Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...]
     
 0.482
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
  
 0.468
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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