Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dapB-2Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113. (359 aa)    
Predicted Functional Partners:
ABK72063.1
Dihydrodipicolinate synthase; Identified by match to protein family HMM PF00701; Belongs to the DapA family.
     
 0.984
dapA
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
     
 0.983
ABK75999.1
Dihydrodipicolinate synthetase; Identified by match to protein family HMM PF00701; Belongs to the DapA family.
     
 0.980
dapD
Tetrahydropicolinate succinylase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA.
     
  0.966
ABK75049.1
Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355.
 
     0.955
dapB-3
Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate.
    
  0.936
dapB-4
Dihydrodipicolinate reductase, N-terminus domain protein; Identified by match to protein family HMM PF01113; match to protein family HMM PF01408; match to protein family HMM PF02629.
  
   
 0.908
dapE
Succinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls.
      
 0.768
ABK72581.1
Hypothetical protein; Identified by Glimmer2; putative.
  
     0.725
ABK69806.1
Putative transcriptional regulator; Identified by match to protein family HMM PF00440.
       0.724
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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