Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK75621.1Metallo-beta-lactamase superfamily protein; Identified by match to protein family HMM PF00753. (248 aa)    
Predicted Functional Partners:
fgd
F420-dependent glucose-6-phosphate dehydrogenase; Catalyzes the coenzyme F420-dependent oxidation of glucose 6- phosphate (G6P) to 6-phosphogluconolactone. Appears to have a role in resistance to oxidative stress, via its consumption of G6P that serves as a source of reducing power to combat oxidative stress in mycobacteria. Cannot use NAD, NADP, FAD or FMN instead of coenzyme F420 as an electron acceptor. Exhibits nearly no activity with D-mannose-6- phosphate or D-fructose-6-phosphate as substrate. Belongs to the F420-dependent glucose-6-phosphate dehydrogenase family.
     
 0.723
ABK75667.1
Identified by match to protein family HMM PF00581; match to protein family HMM PF00753.
  
 0.588
ABK69677.1
Molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.
  
 0.532
ABK75967.1
Identified by match to protein family HMM PF00753.
      
 0.532
ABK76104.1
Rhodanese-like domain protein; Identified by match to protein family HMM PF00581.
 
 0.520
ABK69553.1
Identified by match to protein family HMM PF00753.
     
  0.491
ABK74743.1
Identified by match to protein family HMM PF00903.
  
 0.490
ABK71032.1
Identified by match to protein family HMM PF00753.
  
  
  0.449
ABK71920.1
Conserved hypothetical protein.
  
 0.438
ABK73818.1
Rhodanese domain protein/cystathionine beta-lyase.
  
 0.438
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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