Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
pknGSerine/threonine protein kinase; Identified by match to protein family HMM PF00069; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (760 aa)    
Predicted Functional Partners:
garA
Forkhead-associated protein; Involved in regulation of glutamate metabolism. Acts as a phosphorylation-dependent molecular switch that modulates the activities of Kgd and Gdh.
 
 
 
 0.995
ABK71181.1
Bacterial extracellular solute-binding protein, family protein 3; Identified by match to protein family HMM PF00497.
 
  
 0.993
ABK73037.1
Putative conserved membrane protein.
 
  
 0.986
ABK72306.1
Protein phosphatase 2C; Identified by match to protein family HMM PF00481.
 
 
 0.800
mmpL11
MmpL11 protein; Contributes to cell wall biosynthesis and biofilm formation. Transports the mycolic acid-containing lipids monomeromycolyl diacylglycerol (MMDAG) and mycolate ester wax (WE) to the bacterial surface.
    
 
 0.774
ABK70127.1
Probable serine/threonine-protein kinase PknB; Identified by match to protein family HMM PF00069; match to protein family HMM PF01163.
  
   
 0.770
ABK75945.1
Identified by match to protein family HMM PF00481.
 
 
 0.756
pknB
Serine-threonine protein kinase; Protein kinase that regulates many aspects of mycobacterial physiology. Is a key component of a signal transduction pathway that regulates cell growth, cell shape and cell division via phosphorylation of target proteins (By similarity). Probably phosphorylates RseA.
 
 
0.730
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
  
  
 0.713
ABK75725.1
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069.
  
   
0.703
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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