Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene co-occurrence
gene fusions
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[Homology]
Score
ABK73037.1Putative conserved membrane protein. (437 aa)    
Predicted Functional Partners:
ABK71181.1
Bacterial extracellular solute-binding protein, family protein 3; Identified by match to protein family HMM PF00497.
 
  
 0.991
pknG
Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
 
  
 0.986
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
     
 0.814
ABK75685.1
Antigen 85-C; Identified by match to protein family HMM PF00756.
 
  
 0.751
ABK69920.1
Antigen 85-C; Identified by match to protein family HMM PF00756.
 
  
 0.734
fbpB
Antigen 85-C; The antigen 85 proteins (FbpA, FbpB, FbpC) are responsible for the high affinity of mycobacteria for fibronectin, a large adhesive glycoprotein. They also help to maintain the integrity of the cell wall by catalyzing the transfer of mycolic acids to cell wall arabinogalactan and through the synthesis of alpha,alpha-trehalose dimycolate (TDM, cord factor). They catalyze the transfer of a mycoloyl residue from one molecule of alpha,alpha-trehalose monomycolate (TMM) to another TMM, leading to the formation of TDM (By similarity).
 
  
 0.726
eccB3
Conserved hypothetical protein; An ATPase (By similarity). Part of the ESX-3 specialized secretion system, which is required for siderophore-mediated iron acquisition and for the secretion of EsxH and EsxG.
  
  
 0.712
ABK70927.1
Antigen 85-A; Identified by match to protein family HMM PF00756.
 
  
 0.709
ABK73138.1
Antigen 85-C; Identified by match to protein family HMM PF00756.
 
  
 0.708
ABK73297.1
Conserved hypothetical protein.
  
     0.692
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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