Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK72519.1Conserved hypothetical protein. (185 aa)    
Predicted Functional Partners:
ABK71844.1
Conserved hypothetical protein; Identified by match to protein family HMM PF04978.
  
   
 0.871
mca
Mycothiol conjugate amidase Mca; A mycothiol (MSH, N-acetyl-cysteinyl-glucosaminyl-inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics. Activity is specific for the mycothiol moiety.
  
   
 0.861
ABK74282.1
Conserved hypothetical protein.
       0.815
ABK69967.1
Conserved hypothetical protein; Identified by match to protein family HMM PF04978.
      
 0.809
dinB-2
DNA polymerase IV; Identified by match to protein family HMM PF00817.
     
 0.807
ABK75481.1
Succinic semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
       0.747
ABK70317.1
Conserved hypothetical protein.
     
 0.733
ABK73715.1
Conserved hypothetical protein.
       0.603
dinB
DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
     
 0.574
ABK72190.1
Conserved hypothetical protein.
       0.573
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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