Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75900.1Conserved hypothetical protein. (92 aa)    
Predicted Functional Partners:
ABK75703.1
Conserved hypothetical protein.
 
    0.879
ABK73512.1
Phosphate/sulphate permease; Identified by match to protein family HMM PF01384.
 
    0.840
ABK71419.1
Conserved hypothetical protein.
 
     0.703
stf0
Conserved hypothetical protein; Catalyzes the sulfuryl group transfer from 3'- phosphoadenosine-5'-phosphosulfate (PAPS) to trehalose, leading to trehalose-2-sulfate (T2S). The sulfation of trehalose is the first step in the biosynthesis of sulfolipid-1 (SL-1), a major cell wall glycolipid in pathogenic mycobacteria. Cannot use free glucose and unnatural stereoisomers of trehalose (alpha,beta (neo-trehalose) and beta,beta (iso-trehalose)) as substrates.
  
     0.648
ABK73949.1
Conserved hypothetical protein.
  
     0.632
ABK74358.1
Conserved hypothetical protein.
  
     0.627
trpC
Indole-3-glycerol phosphate synthase; Identified by match to protein family HMM PF00218; Belongs to the TrpC family.
   
    0.614
ABK73314.1
Condensation domain protein; Identified by match to protein family HMM PF00668.
  
     0.587
ABK73871.1
Cytosine permease, putative; Identified by match to protein family HMM PF02133.
  
     0.574
ABK70046.1
Conserved hypothetical protein.
  
     0.563
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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