Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ureCUrease, alpha subunit; Identified by match to protein family HMM PF00449; match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR01792. (568 aa)    
Predicted Functional Partners:
ABK73901.1
Urease gamma/beta subunit; Identified by match to protein family HMM PF00547; match to protein family HMM PF00699; match to protein family HMM TIGR00192; match to protein family HMM TIGR00193.
 0.999
ureB
Urease, beta subunit; Identified by match to protein family HMM PF00699; match to protein family HMM TIGR00192; Belongs to the urease beta subunit family.
 0.999
ureA
Urease, gamma subunit; Identified by match to protein family HMM PF00547; match to protein family HMM TIGR00193; Belongs to the urease gamma subunit family.
 0.996
ABK72983.1
Urease accessory protein UreF; Identified by match to protein family HMM PF01730.
 
 
 0.975
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.965
ureD
Urease accessory protein UreD, putative; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.948
ABK74523.1
Urease accessory protein UreE 1; Identified by match to protein family HMM PF02814.
  
  
 0.881
ABK71104.1
Urea amidolyase; Identified by match to protein family HMM PF02626; match to protein family HMM PF02682; match to protein family HMM TIGR00724.
    
 0.865
ureG-2
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
  
 0.850
alc
Allantoicase; Identified by match to protein family HMM PF03561; match to protein family HMM TIGR02961; Belongs to the allantoicase family.
    
  0.842
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: medium (46%) [HD]