Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ABK74033.1Isonitrile hydratase, putative; Identified by match to protein family HMM PF01965. (243 aa)    
Predicted Functional Partners:
ABK73246.1
Transcriptional regulator, AraC family protein; Identified by match to protein family HMM PF00165; match to protein family HMM PF01965.
 
    
0.813
ABK75828.1
Hydrolase, alpha/beta fold family protein; Identified by match to protein family HMM PF00561.
  
    0.801
menD
2-oxoglutarate decarboxylase; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).
       0.800
ABK74778.1
Probable conserved transmembrane protein.
       0.800
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.517
ABK75155.1
Transcriptional regulator; Identified by match to protein family HMM PF00165.
 
 
 0.443
ABK75267.1
Transcriptional regulator, AraC family protein; Identified by match to protein family HMM PF00165; match to protein family HMM PF02311.
 
 
 0.439
ABK71788.1
Transcriptional regulatory protein; Identified by match to protein family HMM PF00165.
 
 
 0.439
ABK76117.1
Probable transcriptional regulator, AraC family protein, putative; Identified by match to protein family HMM PF00165.
 
 
 0.422
ABK75141.1
Identified by match to protein family HMM PF00903.
 
    0.415
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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