Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
ABK69599.1Identified by match to protein family HMM PF02133; Belongs to the purine-cytosine permease (2.A.39) family. (478 aa)    
Predicted Functional Partners:
hutF
Formiminoglutamate deiminase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969; match to protein family HMM TIGR02022.
  
  
 0.592
hutU
Urocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate.
  
    0.482
hutH
Histidine ammonia-lyase; Identified by similarity to EGAD:14121; match to protein family HMM PF00221; match to protein family HMM TIGR01225.
  
  
 0.446
pyrB
Aspartate carbamoyltransferase; Identified by match to protein family HMM PF00185; match to protein family HMM PF02729; match to protein family HMM TIGR00670; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
    0.445
ABK73057.1
Phosphomethylpyrimidine kinase.
  
  
 0.438
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
  
  
 0.438
carB
Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02655; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family.
   
  
 0.434
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
  
 0.433
ABK70084.1
Hydroxydechloroatrazine ethylaminohydrolase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
  
  
 0.431
ABK74942.1
Guanine deaminase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
  
  
 0.431
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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