Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK70084.1Hydroxydechloroatrazine ethylaminohydrolase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969. (452 aa)    
Predicted Functional Partners:
ABK71129.1
Transthyretin; Identified by match to protein family HMM PF00576; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
  
 0.919
ABK76140.1
Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin.
 
  
 0.906
ABK71365.1
Allantoicase.
 
     0.893
ABK72488.1
Putative oxidoreductase; Identified by match to protein family HMM PF00111; match to protein family HMM PF01315; match to protein family HMM PF01799; match to protein family HMM PF02738.
 
 
 0.876
ABK73388.1
Identified by match to protein family HMM PF00860; match to protein family HMM TIGR00801.
 
  
 0.864
ABK74849.1
FAD binding domain in molybdopterin dehydrogenase protein; Identified by match to protein family HMM PF00941.
 
 
 0.849
ABK74942.1
Guanine deaminase; Identified by match to protein family HMM PF01979; match to protein family HMM PF07969.
 
    
0.844
mtaP
Methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.805
ABK69811.1
Conserved hypothetical protein; Identified by match to protein family HMM PF02578; match to protein family HMM TIGR00726; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.780
ABK71738.1
Pyrimidine-specific ribonucleoside hydrolase RihA; Identified by match to protein family HMM PF01156.
 
 
 0.624
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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