Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK70951.1Conserved hypothetical protein; Identified by match to protein family HMM PF07848; match to protein family HMM PF08223. (245 aa)    
Predicted Functional Partners:
ABK76145.1
enoyl-CoA hydratase; Identified by match to protein family HMM PF00378.
     
 0.866
ABK70216.1
enoyl-CoA hydratase; Identified by match to protein family HMM PF00378; Belongs to the enoyl-CoA hydratase/isomerase family.
     
 0.866
ABK74895.1
Putative acyl-CoA dehydrogenase; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF08028.
  
    0.742
ABK72706.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
    0.719
ABK73067.1
Putative transcriptional regulator; Identified by match to protein family HMM PF01638.
   
  
 0.674
ABK75039.1
Probable transcriptional regulatory protein; Identified by match to protein family HMM PF00440.
   
    0.668
sir2
NAD-dependent deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.
   
    0.667
ABK75535.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family.
   
    0.653
ABK72430.1
Transcriptional regulator, TetR family protein; Identified by match to protein family HMM PF00440.
  
    0.622
ABK74597.1
Transcriptional regulator; Identified by match to protein family HMM PF03816; match to protein family HMM TIGR00350.
   
    0.617
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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