Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK75130.1Arylsulfatase; Identified by match to protein family HMM PF00884. (783 aa)    
Predicted Functional Partners:
ABK75199.1
Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.
 
   0.951
ABK71897.1
Sulfatase-modifying factor 1; Identified by match to protein family HMM PF03781.
 
   0.872
rpoB
DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. This subunit often mutates to generate rifampicin (Rif) resistance. Interaction with RbpA partially restores Rif-inhibited transcription; once the subunit is Rif-resistant however RbpA no longer stimulates transcription.
   
 
 0.734
ABK75054.1
Identified by match to protein family HMM PF00753.
   
 0.672
ABK73383.1
Conserved hypothetical protein; Identified by match to protein family HMM PF06742; match to protein family HMM PF06863.
 
     0.665
ABK71307.1
Identified by match to protein family HMM PF00884.
 
 
  0.662
ABK73930.1
Sulfatase; Identified by match to protein family HMM PF00884.
 
  
 
0.649
ABK73717.1
Hypothetical protein; Identified by Glimmer2; putative.
       0.608
ABK74932.1
Conserved hypothetical protein.
 
     0.545
ABK75687.1
RNA pseudouridine synthase family protein; Identified by match to protein family HMM PF00849.
  
  
 0.510
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (38%) [HD]