Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK76098.15-oxovalerate dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (480 aa)    
Predicted Functional Partners:
ABK70515.1
NADP-dependent fatty aldehyde dehydrogenase; Identified by match to protein family HMM PF00171.
     
 0.843
ABK73285.1
Pyridine nucleotide-disulphide oxidoreductase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
  
 
 0.821
ABK70473.1
Translation initiation inhibitor; Identified by match to protein family HMM PF01042.
  
 0.810
ABK73400.1
Rieske [2Fe-2S] domain protein; Identified by match to protein family HMM PF00355.
  
 
 0.809
ABK76182.1
Gamma-glutamyltranspeptidase; Identified by match to protein family HMM PF01019.
  
 
 0.799
ABK70445.1
Ferredoxin; Identified by match to protein family HMM PF00355.
  
 
 0.779
pks
Type I modular polyketide synthase; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF00698; match to protein family HMM PF01370; match to protein family HMM PF02801.
  
 0.762
ABK70616.1
Identified by match to protein family HMM PF03070.
 
  
 0.729
ABK72679.1
Toluate 1,2-dioxygenase electron transfer component; Identified by match to protein family HMM PF00106; match to protein family HMM PF00111; match to protein family HMM PF00175; match to protein family HMM PF00970; match to protein family HMM PF07729; match to protein family HMM PF08021.
  
 0.721
sucA
2-oxoglutarate dehydrogenase, E1 component; Shows three enzymatic activities that share a first common step, the attack of thiamine-PP on 2-oxoglutarate (alpha-ketoglutarate, KG), leading to the formation of an enamine-thiamine-PP intermediate upon decarboxylation. Thus, displays KGD activity, catalyzing the decarboxylation from five-carbon 2-oxoglutarate to four-carbon succinate semialdehyde (SSA). Also catalyzes C-C bond formation between the activated aldehyde formed after decarboxylation of alpha- ketoglutarate and the carbonyl of glyoxylate (GLX), to yield 2-hydroxy- 3-oxoadipate [...]
  
 0.675
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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