Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
sppASignal peptide peptidase SppA, 67K type; Identified by match to protein family HMM PF01343; match to protein family HMM TIGR00705; match to protein family HMM TIGR00706. (594 aa)    
Predicted Functional Partners:
ABK71197.1
ATPase.
      
 0.824
ABK72779.1
Hypothetical protein; Identified by Glimmer2; putative; Belongs to the WXG100 family.
      
 0.761
ABK70459.1
Conserved hypothetical protein.
      
 0.761
ABK70364.1
1-acylglycerol-3-phosphate O-acyltransferase; Identified by match to protein family HMM PF01553.
  
  
 0.704
ABK73942.1
GntR-family protein transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07729.
      
 0.676
ABK75535.1
RNA polymerase sigma-70 factor; Identified by match to protein family HMM PF04542; match to protein family HMM PF04545; match to protein family HMM TIGR02937; Belongs to the sigma-70 factor family.
  
  
 0.661
ABK75553.1
Hypothetical protein; Identified by Glimmer2; putative.
     
 0.627
ABK71598.1
Conserved hypothetical protein; Identified by match to protein family HMM PF00296.
       0.577
fni
Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).
     
 0.548
ABK74616.1
Cyclopropane-fatty-acyl-phospholipid synthase; Identified by match to protein family HMM PF02353.
      
 0.541
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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