Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK69695.1Histidinol-phosphate aminotransferase 2; Identified by match to protein family HMM PF00155. (337 aa)    
Predicted Functional Partners:
hisB
Imidazoleglycerol-phosphate dehydratase; Identified by match to protein family HMM PF00475.
 
 0.998
ABK71789.1
Prephenate dehydrogenase; Identified by match to protein family HMM PF02153.
  
 
 0.979
ABK75787.1
Inositol monophosphatase; Identified by match to protein family HMM PF00459; match to protein family HMM TIGR02067.
  
 
 0.971
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
 
 0.956
pheA
Prephenate dehydratase; Identified by match to protein family HMM PF00800; match to protein family HMM PF01842.
  
 
 0.950
hisC-2
Histidinol-phosphate aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.
  
  
0.949
hisC
Histidinol-phosphate aminotransferase; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 
0.948
ABK69697.1
Isochorismate synthase DhbC; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00543.
    
 0.940
hisF
Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.
 
 
 0.924
ABK75279.1
Cyclohexadienyl dehydratase; Identified by match to protein family HMM PF00497.
    
 0.914
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.