Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mmsB3-hydroxyisobutyrate dehydrogenase; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807; match to protein family HMM TIGR01692; Belongs to the HIBADH-related family. (290 aa)    
Predicted Functional Partners:
mmsA
Methylmalonate-semialdehyde dehydrogenase; Identified by similarity to GB:AAA99190.1; match to protein family HMM PF00171; match to protein family HMM TIGR01722.
 
 
 0.995
mmsA-2
Methylmalonate-semialdehyde dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01722.
 
 
 0.977
ABK74368.1
acyl-CoA dehydrogenase family protein member 8; Identified by match to protein family HMM PF00441; match to protein family HMM PF02770; match to protein family HMM PF02771; match to protein family HMM PF08028.
 
 
 0.966
ABK72245.1
6-phosphogluconate dehydrogenase, NAD-binding; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807.
  
  
 
0.950
ABK71291.1
Acetyl-/propionyl-coenzyme A carboxylase alpha chain; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02222; match to protein family HMM PF02785; match to protein family HMM PF02786.
  
 
 0.947
ABK74974.1
Coniferyl aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 
 0.947
ABK71302.1
6-phosphogluconate dehydrogenase, NAD-binding; Identified by match to protein family HMM PF03446; match to protein family HMM PF03807.
  
  
 
0.947
ABK72254.1
enoyl-CoA hydratase; Identified by match to protein family HMM PF00378.
 
 0.946
ABK71023.1
Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 
 0.945
ABK69681.1
Aldehyde dehydrogenase (NAD) family protein; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 
 0.945
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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