Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ABK73012.1Cupin domain protein; Identified by match to protein family HMM PF07883. (187 aa)    
Predicted Functional Partners:
ABK74011.1
Hypothetical protein; Identified by Glimmer2; putative.
  
    0.778
groL-2
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
       0.627
alr
Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family.
  
    0.535
nnrD
Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repa [...]
  
  
 0.509
ABK76090.1
Cupin domain protein; Identified by match to protein family HMM PF07883.
 
   
 0.476
groS
Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
       0.453
ABK74367.1
Transcriptional regulator, GntR family protein; Identified by match to protein family HMM PF00392; match to protein family HMM PF02082; match to protein family HMM PF07702.
  
  
 0.424
ABK71748.1
GntR-family protein transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
  
  
 0.424
phnF
GntR-family protein transcriptional regulator; Represses the phnDCE operon, involved in the uptake of phosphate, under conditions of phosphate availability in the cell.
  
  
 0.424
ABK72103.1
Putative transcriptional regulator; Identified by match to protein family HMM PF00392; match to protein family HMM PF07702.
  
  
 0.424
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
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