Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ABK74788.1Conserved hypothetical protein; Identified by match to protein family HMM PF05331. (121 aa)    
Predicted Functional Partners:
ABK75489.1
Identified by match to protein family HMM PF03029.
 
  
 0.994
ABK72510.1
Periplasmic sensor signal transduction histidine kinase; Identified by match to protein family HMM PF00672; match to protein family HMM PF02518.
 
 0.985
ABK73273.1
Roadblock/LC7 domain protein; Identified by match to protein family HMM PF03259.
 
  
 0.976
mfpA
Conserved hypothetical protein; When present on multicopy plasmids confers increased resistance to fluoroquinolone antibiotics such as ciprofloxacin and sparfloxacin but not the quinolone nalidixic acid. Forms a structure that exhibits size, shape and electrostatic similarity to B-form DNA; it may bind to DNA gyrase which is postulated to protect it from fluoroquinolones (By similarity). Belongs to the pentapeptide repeat protein family.
  
  
 0.950
ABK75990.1
Putative 3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00378; match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.760
ABK70103.1
Fatty acid synthase; Identified by match to protein family HMM PF00109; match to protein family HMM PF00698; match to protein family HMM PF01575; match to protein family HMM PF02801.
  
 0.661
ABK71785.1
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.633
ABK72206.1
hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.633
ABK75159.1
3-hydroxyacyl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.633
ABK71837.1
3-hydroxybutyryl-CoA dehydrogenase; Identified by match to protein family HMM PF00725; match to protein family HMM PF02737.
  
 0.633
Your Current Organism:
Mycolicibacterium smegmatis
NCBI taxonomy Id: 246196
Other names: M. smegmatis MC2 155, Mycobacterium smegmatis MC2 155, Mycolicibacterium smegmatis MC2 155
Server load: low (40%) [HD]